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DNA ligase 3: complexes with DNA repair protein XRCC1 to assist in sealing DNA through the whole process of nucleotide excision maintenance and recombinant fragments. From the all identified mammalian DNA ligases, only ligase three continues to be located being existing in mitochondria.
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Adenylylation (addition of AMP) of a lysine residue while in the Energetic center from the enzyme, pyrophosphate is launched;
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